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Special Collection: Academic Screening Centers and Translational Drug Discovery Centers Showcase

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Guest Editor Marc Bickle, Ph.D.
Technology Development Studio
Max Planck Institute of Molecular Cell Biology and Genetics
Dresden, Germany

 

This special issue of SLAS Discovery showcases academic screening centers and not-for-profit translational drug discovery centers. Historically, high-throughput screening was developed by the pharmaceutical industry and until the end of the 20th century was mainly carried out within its walls. After the sequencing of the human genome, academic institutions started creating screening centers to either find tool compounds or carry out RNA interference screens to study the genome.

Nine original research articles and six review articles are included in the special issue, offering a snapshot of the research being conducted in academic screening laboratories and translational drug discovery centers. The articles cover a wide range of topics – from neglected diseases technology to data mining to a label-free kinetic profiling method. The institutions featured are:

  • Amsterdam Institute for Molecules, Medicines and Systems, Vrije Universiteit Amsterdam (Amsterdam, the Netherlands)
  • CellNetworks Advanced Biological Screening Core Facility, Heidelberg University (Heidelberg, Germany)
  • Centre for Integrative Biology High-Throughput Screening and Validation, University of Trento, (Trento, Italy)
  • Chemical Biology Consortium, Karolinska Institutet (Stockholm, Sweden)
  • Chemical Biology and Therapeutics Group, Lund University (Lund, Sweden)
  • Drug Discovery Initiative, University of Tokyo (Tokyo, Japan)
  • Edinburgh Cancer Discovery Unit, University of Edinburgh (Scotland, United Kingdom)
  • EU-OPENSCREEN (European Union)
  • Fraunhofer-Institute IME (Hamburg, Germany)
  • Helmholtz Centre for Infection Research (Braunschweig, Germany)
  • LifeArc (Stevenage, UK)
  • Moulder Center for Drug Discovery Research, Temple University School of Pharmacy (Philadelphia, PA, USA)
  • Pharmacy Chemical Biology Center, University of Pittsburgh School of Pharmacy (Pittsburgh, PA, USA)
  • Scripps Research Molecular Screening Center (Jupiter, FL)
  • Stem Cell Hotel, Centre for Stem Cells and Regenerative Medicine, King's College (London, UK)
  • Technology Development Studio of the Max Planck Institute of Molecular Cell Biology and Genetics (Dresden, Germany)

SLAS publishes two PubMed:MEDLINE-indexed journals and accepts manuscripts on an ongoing basis from members and non-members.  > READ MORE

February 20, 2019