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Editorial Archive

December 28, 2015
Accelerating Excellence in Life Sciences Discovery & Technology: The 2015 SLAS Annual Report

SLAS is a collaborative community that brings together creative visionaries and fearless pioneers whose ingenuity and innovation are reshaping the world and changing the way we think. SLAS members are some of today's most accomplished scholars, scientists, innovators and entrepreneurs. They're creative problem solvers, collaborators and over-achievers. They celebrate their diversity and find a provocative home base in SLAS. I invite you to meet some of them.

December 21, 2015
Screening Strategies for Drug Discovery: Matching Tools with Solutions

"The focus should always be on identification of medicines for the patients. Phenotypic approaches and target-based approaches provide different strategies and tools in the drug discovery tool box. It is important to know what tools are available and know how to effectively use the tools, so that the appropriate tool is selected and used in an efficient manner." This is the overarching drug discovery guidance given by David Swinney, co-instructor for the new SLAS Short Course, "Screening Strategies for Drug Discovery: Matching Tools with Solutions."

December 7, 2015
Effective Drug Discovery Begins with the Right Assay

"The amount of time assay development can take is often not appreciated," says Nathan Coussens, U.S. National Institutes of Health (NIH) research scientist. "The results from multiple assays are needed to interpret the results of any one assay, which multiplies the amount of work. Rigor in developing the best possible assays with well-separated high and low controls is very important."

November 30, 2015
From Burettes to Pipettes to Robots: Master Liquid Handling Basics for Peak Performance

Congratulations! You've landed a great new job in a facility that has a tool that's new to you – an automated liquid handler. This tool has the potential to increase both your output and accuracy – if you know how to use it.

November 23, 2015
Using Functional Metagenomics to Unearth Bacterial Effectors in the Human Gut

As a practicing gastroenterologist at Mount Sinai Hospital in New York City, Louis Cohen, M.D., was driven to understand how commensal bacteria interacted with host cells in inflammatory bowel disease, Crohn's disease and ulcerative colitis. As a researcher in the laboratory of Sean Brady, Ph.D. at The Rockefeller University, NYC, he found answers.

November 2, 2015
Dino Di Carlo: Connecting Science Fiction, Science Fact and Science Future

Lured into science by fiction stories filled with ingenious feats of genetic engineering, SLAS2016 Co-Chair and JALA Reviews Editor Dino Di Carlo, Ph.D., later pursued bioengineering because of its opportunity to touch the future with today's research.

October 12, 2015
Steve Rees: Learning and Collaboration are Key to Great Science

Whether it's bonding with family during an elephant ride in India or joining forces with fellow scientists in research collaborations, Steve Rees wants to forge lasting relationships and motivate others both inside and outside of the laboratory.

October 5, 2015
Win-Win: SLAS and Keck Graduate Institute Collaborate on JALA Special Issue

Students from the Keck Graduate Institute School of Applied Life Sciences put their best work forward in the October 2015 special issue of the Journal of Laboratory Automation (JALA) on In Vitro Diagnostic Technology Reviews. The rigor of the peer review and revision process boosted their professional experience and career confidence and resulted in a meaningful special issue for the life sciences R&D and technology community.

September 21, 2015
Empowering the Innovators: SLAS Graduate Education Fellowship Grant Program

The new SLAS Graduate Education Fellowship Grant Program is one more way SLAS lives its mission to advance the field of life sciences R&D by fostering the next generation of professional scientists.

September 4, 2015
Gene Editing Technology with CRISPR-Cas9: What Life Sciences Researchers Need to Know

"I remember the first time I heard of CRISPR—reading the summary of a paper published in Science by Jennifer Doudna of the University of California, Berkeley and colleagues. It was one of those 'Oh my' moments. I saw the power and potential of the technology for functional genomics, and knew immediately that it was something I needed to be doing," says John Doench, Ph.D., a research scientist in the Broad Institute's RNAi Platform.

August 31, 2015
RNAi on the Rebound: What Life Sciences R&D Professionals Need to Know

RNAi is undergoing a "renaissance," according to the guest editors of the September 2015 JBS Special Issue on Screening by RNAi and Precise Genome Editing Technologies. The proof is in the issue's carefully selected papers, which reveal novel approaches and bioinformatics tools that are reducing the off-target effects and other problems that have caused researchers to question the value of the technology in the past.

August 7, 2015
Biosensors Go Global: JALA Special Issue Reports Innovations from Around-the-World

"Biosensing is a hot research trend, especially in China where the technology is important to every major aspect of our daily lives," says Xianting Ding, Ph.D., School of Biomedical Engineering, Institute for Personalized Medicine, Shanghai Jiao Tong University. "Now we see it starting to make a difference in all parts of the world, and in disciplines as diverse as disease diagnosis, environmental monitoring, food engineering and drug discovery."

July 31, 2015
Laboratory Purchasing Trends 2015: Uptick Expected

While not rebounding to 2011 levels, the survey responses obtained from the 2015 North American Survey of Laboratory Purchasing Trends generally point to a bit more optimism, fueled by increased project work across several industry sectors.

July 20, 2015
Barry Bunin: Reading, Writing & Rounding Up Research

Before The Cloud was a regular part of our lexicon, entrepreneurs such as Barry Bunin pioneered secure, collaborative data hosting for scientists.

July 13, 2015
Seek Mentors to Enhance Your Career

Yongtao was seeking a full time position after earning his Ph.D. First, he sought coaching on how to compose targeted resumes for applications. Then, he wondered how he should prepare for interviews, so he enrolled in a professional development course and learned about the interviewing continuum where he practiced several in-person and remote interview styles.

June 15, 2015
Armin Nourani: Seek the Critique

His approach might not be for the faint-of-heart, but Armin Nourani doesn't simply wonder what went wrong when he faces a rejection letter. He seeks out answers.

June 1, 2015
SLAS2015 Student Poster Winners: Transformed by Science

Young careers take flight as students gain valuable experience and exposure to laboratory science and technology professionals at all levels via the annual SLAS Student Poster Competition.

May 22, 2015
2015 SLAS Innovation Award Winner Jonathan Wingfield: Bringing Screening with Mass Spectrometry to the Next Level

Science has intrigued Jonathan Wingfield, principal scientist, AstraZeneca, UK, since he was a boy, which is why he obtained a Ph.D. in microbiology. But something happened during his post-doc at Children's Hospital in Cincinnati, OH, that convinced Wingfield to reconsider his decision to pursue basic academic research, and ultimately led to his being honored as the 2015 SLAS Innovation Award winner.

May 11, 2015
2015 SLAS Leadership Forum: Rethinking the U.S. Biomedical Research Model

Is the U.S. biomedical research system broken? If so, what can be done to fix it? Participants in the first-ever SLAS Leadership Forum grappled with these questions in a two-hour discussion held during SLAS2015 in Washington, DC.

April 27, 2015
Biologics Come of Age: Therapeutic Antibody Discovery and Development

Making advancements in a scientific field requires continual learning, extreme curiosity and just plain old hard work. To fuel their interest in the expanding field of biologics in drug discovery, Rob Howes, Ph.D., and Joseph G. McGivern, Ph.D., took on volunteer roles as Journal of Biomolecular Screening (JBS) guest editors for the April 2015 Special Issue on Therapeutic Antibody Discovery and Development.