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Using Fragment-Based Approaches to Discover New Antibiotics

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Roderick E. Hubbard
Professor, University of York
Senior Fellow, Vernalis (R&D) Ltd.
United Kingdom


Professor Rod Hubbard has been an academic at the University of York (Heslington, York U.K.) for more than 35 years, working with methods for analysis and exploitation of protein structure. Hubbard developed molecular graphics and modeling methods in the 1980s, some of which remain in use today and helped build structural biology at York during the 1980s and 1990s. He worked on the structure of many proteins of therapeutic importance combined with studies of protein-ligand interactions and methods in structure-based design. In 1997, he was a founding member of the structure-based pharmaceutical company that became Vernalis. Since 2001, he has split his time between Vernalis (fragment and structure-based drug discovery) and York (fragment methods for chemical biology and industrial biotechnology). In addition, he works with U.K. Research Councils and consults with pharmaceutical and technology companies around the world.


SLAS publishes two PubMed:MEDLINE-indexed journals and accepts manuscripts on an ongoing basis from members and non-members.  > READ MORE

June 20, 2018