This track will focus on recent innovations across the assay development and screening discipline, including the adoption of novel technologies and the implementation of effective, innovative screening campaigns and hit triage strategies. Attendees will learn about the development of robust, physiologically relevant biochemical, biophysical and cellular assays that are crucial for identifying novel biology, targets, and modalities that engage these targets. There will be an emphasis on recent case studies of cutting-edge assay, predictive, and perturbation approaches that have increased the success rates of target discovery and lead identification. The track will also highlight emerging approaches that have been coupled with next-generation therapeutic modalities and novel mechanisms of action to broaden the scope of target classes that can be drugged. Taken together, the overall track will highlight advances in the fields of assay development and screening that enhance efforts to identify, validate and characterize novel targets and potential lead molecules.