April 28, 2026
April 28, 2026
CRISPR-mediated gene activation (CRISPRa) efficiently mimics physiological gene overexpression, yet traditional arrayed plasmid and lentiviral library production and screening remain labor-intensive and costly to scale.
In this webinar presented by Beckman Coulter Life Sciences, we’ll discuss the automated workflows we adopted to overcome these bottlenecks and the limitations of conventional cell culture in fast-growing models, using the Biomek i7 Hybrid platform integrated with multiple instruments. Managed by intuitive SAMI EX software, this workstation streamlines arrayed plasmid miniprep, lentivirus production, and CRISPRa screening by automating cell library passaging. Building on these easily customizable and highly adaptable workflows, we accelerate high-throughput siRNA, Open Reading Frame (ORF), and small-molecule library screens, enable flexible scalability for lentiviral/retroviral and rAAV production, and facilitate the establishment of mutagenesis-driven clonal lines for advanced functional genomics applications.
Chun-Teng Huang, MS
Director, Functional Genomics Core Facility
(Sanford Burnham Prebys Medical Discovery Institute)
At Beckman Coulter Life Sciences, we are partners in time. We accelerate answers to critical questions through the power of efficiency, saving hours from some workflows and delivering reliable outcomes in liquid handling, genomics, flow cytometry, particle analysis/counting, and centrifugation.
Chun-Teng Huang, MS, joined Sanford Burnham Prebys in 2008 and has accumulated extensive expertise in functional genomics and viral vector technologies. He has over 12 years of experience managing the Viral Vector Core, 7 years supervising the Training and Educational Laboratory, and 5 years serving as Director of the Functional Genomics Core Facility, supported by an NCI Cancer Center Support Grant (P30 CA030199). In addition to his primary specialization in exosomes and viral vectors, including lentivirus, retrovirus, adenovirus, adeno-associated virus, sindbis virus, zika virus, and vesicular stomatitis virus, Mr. Huang has developed broad skill sets and customized services in CRISPR/Cas technologies, high-throughput automation, stem cell cultivation, and pooled and arrayed gene perturbation library screening.
He has collaborated with numerous research laboratories and coauthored more than 20 publications addressing cancer and other human diseases. With the recent acquisition of the NIH S10-awarded Biomek i7 Hybrid automated workstation (S10 OD036254), he has established high-throughput, automated workflows that streamline arrayed mammalian cell cultivation, plasmid minipreparation, lentivirus production, and CRISPR library screening on the Biomek i7 platform, resulting in four preprint publications as corresponding author since October 2025.