Call for Papers

SLAS Discovery: Now Accepting Protocols

Special issue proposals accepted until June 15!

Submit Proposal

SLAS Discovery is pleased to introduce a new Protocols article type (see article type details in our Guide for Authors). In summary, the intent is to focus on step-by-step descriptions of methods which enable scientists across academic and industry to directly reproduce the protocol and adapt to their research needs.

Methods published as part of a full research article often lack sufficient detail necessary to easily recreate the experiment(s) and analysis. To address this gap, SLAS Discovery Protocols now allow authors to publish these methods in full detail, thereby providing much-needed reproducibility and rigor of methods. To inaugurate the release of Protocols, we have devoted a Special Issue to the novel format. In the future, Protocols will be a standard article type for SLAS Discovery and will be published Open Access.

SLAS Discovery Guest Editor(s) Mariafrancesca Scalise Ph.D., (University of Calabria) and Adam Zweifach Ph.D. (University of Connecticut) invite the submission of abstracts of validated experimental protocols for publication in a 2022 Special Issue. Manuscript proposals (abstracts) will be used to select and invite protocols for review and publication consideration.

Drs. Scalise and Zweifach seek high-quality and validated protocols on methods that have been previously used in published and peer-reviewed scientific studies. Protocols not used previously will only be considered if experimental data demonstrating the feasibility and efficacy of the method is submitted. Abstracts are welcome from academia, industry and service providers. Methods will need to be in scope with the Journal and include, but are not limited to:

  • High-throughput transfection protocols of primary or stem cells
  • Primary screening of primary cells, e.g., endocrine, cancer, neuroscience targets
  • Automated cultivation of cells, stem cells, organoids and other 3D models, including lab-on-a-chip
  • Methods enabling exploration of biology in 3D
  • High-throughput/high-content imaging and image analysis
  • Data analysis and/or computational protocols for high-throughput/high-content screening data, including deep learning and AI approaches
  • Detailed screening assay methodology for identifying novel targets (e.g., CRISPR, si/shRNA) or compounds
  • Target validation protocols
  • Target engagement protocols
  • High-throughput/high-content methods for v5ADME/PK/toxicology
  • Methods for identification and validation (preclinical and/or clinical) of target relevant biomarkers, including gene expression, e.g., fluorescent in situ hybridization.
  • Allosteric modulators of kinases, GPCRs, NHRs, etc., protacs and degraders

Abstracts are due June 15. Proposals should include your name, contact information, affiliation, a working title and abstract (250-500 words) as an MS Word document.

Invited manuscripts must be completed and submitted by August 1. All submitted papers will be subject to peer-review to ensure scientific rigor, clarity of expression and integration with other contributions in the SLAS Discovery Special Issue.

Publication note: After submissions are accepted, articles publish online ahead-of-print within 30 days, becoming immediately searchable and citable with a DOI.

Questions? Please e-mail ajump@slas.org or call +1.630.256.7527, ext. 106.

SLAS Discovery Call for Papers: Protease Drug Discovery

Proposals accepted until June 15!

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SLAS Discovery Guest Editors Dr. Jon Ellery, Ph.D and Dr. Nicholas Bland, Ph.D invite the submission of abstracts on topics around protease drug discovery for publication in a 2023 Special Issue. Manuscript proposals (abstracts) will be used to select and invite papers for review and publication consideration.

Drs. Ellery and Bland seek high-quality, short- or full-length research reports, reviews and perspectives related to any aspect of the development of therapeutics directed towards proteases. Abstracts are welcome from academia, industry, and vendors.

Areas of particular interest include, but are not limited to:

  • Protease kinetics and its application to protease drug discovery, including approaches such as single-molecule kinetics.
  • Moving beyond activity assays, for example by utilizing approaches such as biophysics (SPR, GCI, MST, second harmonic generation, etc.) for hit identification, characterization and small molecule optimization for targeting proteases. 
  • New approaches to enzyme directed therapeutics, including modulating non-enzymatic functions of proteases, enzyme activation, biologics, PROTACs, etc.
  • Structure-guided approaches to protease directed drug discovery including computational methodologies as well as experimental techniques including but not limited to X-ray crystallography, NMR and cryo-EM.
  • Examples of successful protease drug discovery efforts that forge a path into new therapeutic areas and what innovations were used to make this happen.
  • Perspectives on the developing landscape of protease drug discovery and the key challenges that are limiting our ability to bring effective therapeutics to the clinic.

Abstracts are due June 15. Proposals should include your name, contact information, affiliation, a working title and abstract (250-500 words) as an MS Word document.

Manuscripts selected for invitation will need to be completed and submitted by August 1. All submitted papers will be subject to peer-review to ensure scientific rigor, clarity of expression and integration with other contributions in the SLAS Discovery Special Issue.

Publication note: After submissions are accepted, articles publish online ahead-of-print within 30 days, becoming immediately searchable and citable with a DOI.

Questions? Please e-mail ajump@slas.org or call +1.630.256.7527, ext. 106.

SLAS Discovery Call for Papers: Early Career Showcase

Submit Proposal

HELP YOUR STUDENTS GET RECOGNIZED FOR THEIR RESEARCH WITH SLAS DISCOVERY.

SLAS Discovery Editor-in-Chief Robert Campbell invites the submission of abstracts from early career researchers for publication in a Special Issue. Existing materials, such as the introductory section of a thesis, can often be built into very successful review and perspective articles by grad students and postdocs. Submitting high-value research accelerates careers, enabling early career researchers to:

  • Build their CVs with high-quality achievements.
  • Heighten their online profiles in PubMed, SCOPUS, Google Scholar, and many other indexing services.
  • Become recognized contributors to a prestigious international research community.

Proposals are due by June 30, 2022. Manuscripts organized as Reviews and Perspectives will be considered with priority.